Barbiturates are popular sedatives and hypnotics whose therapeutic usage has been discontinued since late 1960s owing to the adverse effects of barbiturates. They produce CNS depression in a dose dependent manner starting from sedation, sleep, and anesthesia and finally progressing to coma. The detection of barbiturate can be done by the barbiturate test only if the level of barbiturate in the sample is more than 300ng/ml.
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