Amphetamines were discovered in the end of the 19th century. But it was marketed for therapeutic use only by the beginning of the 20th century when it was found that it is capable of dilating the air sacks in the lungs. It shows structural similarity to the intrinsic hormone adrenaline in our body and proves to be a boon for the people with respiratory distress especially asthma.
It is also effective against hay fever, chronic cold, depression, Parkinson’s disease, narcolepsy, epilepsy, night blindness, ADHD, obesity, impotency, apathy in old age, motion sickness and depression. It is known to alleviate mood as well as allays fatigue. As an appetite suppressant, it is effective against obesity.
Amphetamines have site specific action on the nervous system and improve the performance which has made it popular among college students, athletes, etc. Its use produces an awakening and the person feels good mainly because it acts on the rewarding centers of the brain.
Further, the drug produces tolerance and finally dependence. The mode of producing dependence in case of amphetamine use is by its action on the addiction center on the brain called NUCLEUS ACCUMBENS.
Though it is a restricted drug, yet it is widely used for recreational purposes under various names. One of the most dangerous effects of amphetamine use is that the person may harm people with out any conscience. Behavioral disturbances, tactile hallucinations, loss of behavioral integration and amphetamine psychosis are other problems of chronic amphetamine use.
Drug test for amphetamines, concerta drug test, ritalin drug test are mostly checked for in prescription drug abuse. There are no specific drug testing kits for every brand; however, you got to start from testing for metabolites in ten panel drug screen or in 12 drug test panel and you have to track the metabolite combinations with GC/MS.